The Lions, missing a number of their star players, went down to the Jaguares in their Vodacom Super Rugby clash in Buenos Aires on Saturday.
The Jaguares won 36-24 after leading 21-7 at half-time.
The Jaguares scored four tries by fullback Joaquín Tuculet, wing Ramiro Moyano, centre Jerónimo de la Fuente and flyhalf Nicolás Sánchez.
Sanchez was also on target with two conversions and four penalties for a personal haul of 21 points.
The Lions replied with four tries of their own by No 8 Warren Whiteley (2), replacement prop Jacques van Rooyen and replacement hooker Malcolm Marx.
Rookies flyhalf Shaun Reynolds added a conversion, as did fullback Jaco van der Walt.
The Jaguares picked up four points for their victory and moved to second in the Africa Conference 2, swapping positions with the Lions who left empty-handed and slipped to third.
In next weekend’s Round 4 action, the Lions host the Reds at Ellis Park (Saturday, March 18 at 17:15).